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Using fuzzy logic to adjust plasma concentration based on a two-compartment pharmacokinetic model 会议论文 期刊论文

编号：

064685c3-d428-4cfe-a810-2021604184d0
作者：

Zhao, Lei (1, 2); Shi, Xin Ling ; Zhang, Yu Feng ; Liu, Ya Jie (1, 3)
作者单位：

(1) School of Information Science and Engineering, Yunnan University, Kunming, China (2) School of Science, Kunming University of Science and Technology, Kunming, China (3) Department of Medical Equipment Center, Kunming Medical University, Kunming, China
语种：

英文
会议名称：

Applied Mechanics and Materials
会议地点：

Zhengzhou, Henan, China
收录：
摘要：

In this paper, a closed-loop control system was developed using fuzzy logic to adapt the parameters of a pharmacokinetic (PK) model. The system is based on a two-compartment PK model with first-order rate process of oral administration. The fuzzy logic adaptation scheme uses the error and the change in error as the input variables. The output variable of the fuzzy controller is the scaling factor to adjust the PK parameter. The fuzzy controller adjusted the real situation concentration to the reference value derived from the parameters of population mean data according to the established rule-base. The simulation results show that the controller provides good performance to adjust the concentration with the reference values. 漏 (2013) Trans Tech Publications, Switzerland.
推荐引用方式
GB/T 7714：

Zhao Lei (1 2),Shi Xin Ling (1),Zhang Yu Feng (1), et al. Using fuzzy logic to adjust plasma concentration based on a two-compartment pharmacokinetic model [J].Applied Mechanics and Materials,2013,341-342:1171-1174.
APA：

Zhao Lei (1 2),Shi Xin Ling (1),Zhang Yu Feng (1),Liu Ya Jie (1 3).(2013).Using fuzzy logic to adjust plasma concentration based on a two-compartment pharmacokinetic model .Applied Mechanics and Materials,341-342:1171-1174.
MLA：

Zhao Lei (1 2), et al. "Using fuzzy logic to adjust plasma concentration based on a two-compartment pharmacokinetic model" .Applied Mechanics and Materials 341-342(2013):1171-1174.

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Using fuzzy logic to adjust plasma concentration based on a two-compartment pharmacokinetic model 会议论文 期刊论文

Using fuzzy logic to adjust plasma concentration based on a two-compartment pharmacokinetic model 会议论文期刊论文