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Polymorphism of MDM2 promoter 309 (rs 2279744) and the risk of PCOS 期刊论文

编号：

0d712cb4-19ad-48a8-9f91-24aaec731170
作者：

Chan, Ying#^[1,2]Jiang, Hongguo^[1];Yang, Xiaoling^[2];Li, Dongya^[2];Ma, Lan^[2];Luo, Ying*^[1]Tang, Wenru*^[1]
语种：

英文
期刊：

GYNECOLOGICAL ENDOCRINOLOGY ISSN：0951-3590 2016 年 32 卷 2 期 (136 - 138)
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关键词：

MDM2 PCOS polymorphism
摘要：

This study aimed at evaluating possible association between MDM2 SNP309 polymorphism (rs 2279744) and polycystic ovary syndrome (PCOS). One hundred and twenty-five women with PCOS and two hundred and fifty women without PCOS were collected from the department of reproductive medicine of college hospital in this case-control study. Peripheral blood samples were collected from all participants and DNA was extracted, MDM2 SNP309 polymorphism (rs 2279744) was determined from the 125 cases and 250 controls. Women were grouped into PCOS (n = 125) group and control group (n = 250). Odds ratios (OR) and 95% confidence intervals (CI) were used to evaluate the association between MDM2 SNP309 polymorphism (rs 2279744) and PCOS. The distribution of T allele was significant higher in PCOS cases than controls. MDM2 SNP 309 T allele is associated with PCOS.
推荐引用方式
GB/T 7714：

Chan Ying,Jiang Hongguo,Yang Xiaoling, et al. Polymorphism of MDM2 promoter 309 (rs 2279744) and the risk of PCOS [J].GYNECOLOGICAL ENDOCRINOLOGY,2016,32(2):136-138.
APA：

Chan Ying,Jiang Hongguo,Yang Xiaoling,Li Dongya,&Tang Wenru.(2016).Polymorphism of MDM2 promoter 309 (rs 2279744) and the risk of PCOS .GYNECOLOGICAL ENDOCRINOLOGY,32(2):136-138.
MLA：

Chan Ying, et al. "Polymorphism of MDM2 promoter 309 (rs 2279744) and the risk of PCOS" .GYNECOLOGICAL ENDOCRINOLOGY 32,2(2016):136-138.
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