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Angiotensin-converting enzyme insertion/deletion gene polymorphisms associated with risk of atrial fibrillation: A meta-analysis of 23 case-control studies 期刊论文

编号：

353501b2-c920-44cc-97c5-c1ad2c5fd92c
作者：

Ma, Runwei(马润伟)#^[1]Li, Xiang#^[1]Su, Guoning^[2];Hong, Yunfei^[3];Wu, Xingjian^[4];Wang, Jiyang^[1];Zhao, Ziliang^[1];Song, Yi*^[1]Ma, Shaohong*^[5]
语种：

英文
期刊：

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM ISSN：1470-3203 2015 年 16 卷 4 期 (793 - 800) ; DEC
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关键词：

Angiotensin-converting enzyme atrial fibrillation gene polymorphisms
摘要：

Aims: The renin-angiotensin-aldosterone system is important to the development of atrial fibrillation (AF). A lot of research has focused on the relationship between angiotensin-converting enzyme (ACE) insertion (I) /deletion (D) gene polymorphisms and AF, with inconsistent results. A meta-analysis was carried out to find the correlation between ACE I/D gene polymorphisms and AF.
Methods: Data were extracted from articles published before September 2013 on ACE I/D polymorphisms and AF in Embase, PubMed, WanFangData, and China National Knowledge Infrastructure.
Results: The recessive model found that ACE I/D gene polymorphisms were related to AF (odds ratio (OR) = 1.61, 95% confidence interval (CI) = 1.16-1.72). Subgroup analysis showed a significant association in the recessive model for Asian (OR = 1.40, 95% CI = 1.19-1.80) and Caucasian (OR = 1.42, 95% CI = 1.01-1.99) populations.
Conclusions:ACE I/D gene polymorphisms and AF are significantly related to ethnicity. Individuals with the ACE D/D genotype appear to be at higher risk of AF.
推荐引用方式
GB/T 7714：

Ma Runwei,Li Xiang,Su Guoning, et al. Angiotensin-converting enzyme insertion/deletion gene polymorphisms associated with risk of atrial fibrillation: A meta-analysis of 23 case-control studies [J].JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM,2015,16(4):793-800.
APA：

Ma Runwei,Li Xiang,Su Guoning,Hong Yunfei,&Ma Shaohong.(2015).Angiotensin-converting enzyme insertion/deletion gene polymorphisms associated with risk of atrial fibrillation: A meta-analysis of 23 case-control studies .JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM,16(4):793-800.
MLA：

Ma Runwei, et al. "Angiotensin-converting enzyme insertion/deletion gene polymorphisms associated with risk of atrial fibrillation: A meta-analysis of 23 case-control studies" .JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM 16,4(2015):793-800.
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