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Demographic and clinical differences between early- and late-onset bipolar disorders in a multicenter study in China 期刊论文

编号：

89579871-9e56-4b4a-93a3-ae4bd7ef2e81
作者：

Zhang, Ling#^[1,2,3,4]Yang, HaiChen#^[5]Xu, XiuFeng(许秀峰)#^[6]Fang, YiRu^[7];Yu, Xin^[8,9,10];Tan, QingRong^[11];Li, HuiChun^[12];Ungvari, Gabor S.^[13,14];Ng, Chee H.^[15];Wang, Gang*^[1,2,3]Xiang, YuTao*^[4]
语种：

英文
期刊：

PSYCHIATRY RESEARCH ISSN：0165-1781 2016 年 246 卷 (688 - 691) ; DEC 30
收录：
关键词：

Bipolar disorder Early onset Late onset China
摘要：

Little is known about the demographic and clinical differences between early-onset (EOB) and late-onset bipolar disorders (LOB) in Chinese patients. This multi-center study examined the demographic and clinical characteristics of EOB (521 years) and LOB ( > 21 years) in China. A consecutively recruited sample of 555 patients with bipolar disorder (BD) from 7 psychiatric hospitals and general hospital psychiatric units across China was examined. Patients' demographic and clinical characteristics were collected using a standardized protocol and data collection procedure. There were 181 (34.8%) patients with EOB and 339 (65.2%) with LOB. Univariate analyses revealed that compared to the LOB group, the EOB group were more likely to be older, unemployed, have a longer illness duration, have BD-I and misdiagnosed as schizophrenia but were less likely to be misdiagnosed as major depressive disorder and receiving antidepressants. Multivariate analyses revealed that unemployment and longer duration of illness were independently associated with EOB. The clinical differences between early-onset and late-onset BD patients in China were largely consistent with those found in Western countries. Early-onset BD appear to be associated with poorer outcomes. Prospective studies examining the long-term outcomes in relation to age-at-onset are needed.
推荐引用方式
GB/T 7714：

Zhang Ling,Yang Hai-Chen,Xu Xiu-Feng, et al. Demographic and clinical differences between early- and late-onset bipolar disorders in a multicenter study in China [J].PSYCHIATRY RESEARCH,2016,246:688-691.
APA：

Zhang Ling,Yang Hai-Chen,Xu Xiu-Feng,Fang Yi-Ru,&Xiang Yu-Tao.(2016).Demographic and clinical differences between early- and late-onset bipolar disorders in a multicenter study in China .PSYCHIATRY RESEARCH,246:688-691.
MLA：

Zhang Ling, et al. "Demographic and clinical differences between early- and late-onset bipolar disorders in a multicenter study in China" .PSYCHIATRY RESEARCH 246(2016):688-691.
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