In Minimally Invasive Spine Surgery, X-ray image is very important for the whole operation process, which must be monitored though it. For normal X-ray image, the image quality is not clear and the Operation precision is hard to be guaranteed. In this paper, Several image processing methods has been used to enhanced the quality of the picture, Image enhancement and edge detection methods were used to contrast the effect of image processing. The experiment has been used to show the processing results in different surgery procedures. The result indicate the image processing technology can help doctors to improve the operation accuracy effectively.