Background/objectives The assessment of nutritional status and the quality of life in patients with gastric cancer has become one of the important goals of current clinical treatment. The purpose of this study was to assess the nutritional status in hospitalized gastric cancer patients by using patient-generated subjective global assessment (PG-SGA) and to analyze the influence of nutritional status on the patients' quality of life (QOL). Methods We reviewed the pathological diagnosis of gastric cancer for 2322 hospitalized patients using PG-SGA to assess their nutritional status and collected data on clinical symptoms, the anthropometric parameters (height, weight, body mass index (BMI), mid-arm circumference (MAC), triceps skin-fold thickness (TSF), and hand-grip strength (HGS). We also collected laboratory data (prealbumin, albumin, hemoglobin) within 48 h after the patient was admitted to the hospital. The 30-item European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) was used for QOL assessment in all patients. Results By using PG-SGA, we found 80.4% of the patients were malnourished (score >= 4) and 45.1% of the patients required urgent nutritional support (score >= 9). In univariate analysis, old age (> 65 years, p < 0.001), female (p = 0.007), residence in a village (p = 0.004), a lower level of education (p < 0.001), and self-paying (p < 0.001) were indicated as risk factors of patients with gastric cancer to be suffering from severe malnutrition. There was a negative correlation between PG-SGA and various nutritional parameters (p < 0.05). The quality of life was significantly different in gastric cancer patients with different nutritional status (p < 0.01). Conclusion Malnutrition of hospitalized patients with gastric cancer in China is common and seriously affects the patients' quality of life. The nutritional status should be evaluated in a timely manner and reasonable nutritional intervention should be provided as soon as possible. The PG-SGA was fit for using as a clinical nutrition assessment method, being worthy of clinical application.
[1]Fujian Med Univ, Fujian Canc Hosp, Dept Med Oncol, Canc Hosp, Fuzhou 350014, Fujian, Peoples R China.
[2]First Hosp Jilin Univ, Canc Ctr, Changchun 130021, Jilin, Peoples R China.
[3]Wuhan Univ, Canc Ctr, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China.
[4]Guangxi Med Univ, Dept Gastrointestinal Surg, Affiliated Tumor Hosp, Nanning 530021, Guangxi, Peoples R China.
[5]Sun Yat Sen Univ, Dept Surg, Affiliated Hosp 1, Guangzhou 510080, Guangdong, Peoples R China.
[6]Sichuan Univ, Dept Clin Nutr, West China Hosp, Chengdu 610041, Sichuan, Peoples R China.
[7]Tianjin Med Univ Canc Inst & Hosp, Natl Clin Res Ctr Canc, Dept Gastrointestinal Oncol, Tianjin Key Lab Canc Prevent & Therapy, Tianjin 300060, Peoples R China.
[8]Anhui Med Univ, Dept Nutr & Metab Oncol, Affiliated Prov Hosp, Hefei 230031, Anhui, Peoples R China.
[9]Hebei Med Univ, Dept Clin Nutr, Hosp 1, Shijiazhuang 050031, Hebei, Peoples R China.
[10]Kunming Med Univ, Inst Gastroenterol, Dept Gastrointestinal Surg, Affiliated Hosp 1, Kunming 650032, Yunnan, Peoples R China.
[11]First Peoples Hosp Kashi, Dept Clin Nutr, Xinjiang 844000, Peoples R China.
[12]Chongqing Gen Hosp, Dept Clin Nutr, Chongqing 400014, Peoples R China.
[13]Huizhou Municipal Cent Hosp, Dept Colorectal & Anal Surg, Huizhou 516001, Guangdong, Peoples R China.
[14]Wuhan Univ, Dept Radiat & Med Oncol, Zhongnan Hosp, Wuhan 430071, Hubei, Peoples R China.
[15]Hebei Med Univ, Xingtai Peoples Hosp, Dept Oncol, Xingtai 054031, Hebei, Peoples R China.
[16]Harbin Med Univ, Tumor Hosp, Dept 1, Harbin 150085, Heilongjiang, Peoples R China.
[17]Guangdong Acad Med Sci, Guangdong Gen Hosp, Dept Nutr, Guangzhou 510080, Guangdong, Peoples R China.
[18]Zhengzhou Univ, Dept Oncol, Affiliated Canc Hosp, Zhengzhou 450008, Henan, Peoples R China.
[19]Henan Canc Hosp, Zhengzhou 450008, Henan, Peoples R China.
[20]Cent S Univ, Xiangya Hosp, Dept Gen Surg, Changsha 410008, Hunan, Peoples R China.
[21]Chinese Acad Med Sci, Canc Hosp, Comprehens Oncol Dept, Beijing 100021, Peoples R China.
[22]Zunyi Med Univ, Dept Oncol, Affiliated Hosp, Zunyi 563000, Guizhou, Peoples R China.
[23]Harbin Med Univ, Affiliated Hosp 4, Harbin 150001, Heilongjiang, Peoples R China.
[24]First Peoples Hosp Foshan, Canc Ctr, Foshan 528000, Guangdong, Peoples R China.
[25]Xiamen Univ, Dept Gastrointestinal Tumor Surg, Affiliated Hosp 1, Xiamen 361003, Fujian, Peoples R China.
[26]Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Nutr, Sch Med, Shanghai 200025, Peoples R China.
[27]Tianjin Third Cent Hosp, Dept Nutr, Tianjin 300170, Peoples R China.
[28]Jinan Univ, Dept Surg, Affiliated Hosp 1, Guangzhou 510632, Guangdong, Peoples R China.
[29]Nanjing Univ, Dept Gen Surg, Med Sch, Affiliated Hosp,Nanjing Drum Tower Hosp, Nanjing 210008, Jiangsu, Peoples R China.
[30]Guangxi Med Univ, Dept Gastrointestinal Surg, Affiliated Hosp 1, Nanning 530021, Guangxi, Peoples R China.
[31]Peoples Hosp Guangxi Zhuang Autonomous Reg, Dept Radiat & Med Oncol, Nanning 530021, Guangxi, Peoples R China.
[32]Peking Univ Canc Hosp & Inst, Dept Clin Nutr, Beijing 100142, Peoples R China.
[33]Kunming Med Coll, Tumor Hosp Yunnan Prov, Dept Nutr, Affiliated Hosp 3, Kunming 650118, Yunnan, Peoples R China.
[34]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Surg, Wuhan 430030, Hubei, Peoples R China.
[35]Guangzhou Red Cross Hosp, Dept Nutr, Guangzhou 510220, Guangdong, Peoples R China.
[36]Univ Elect Sci & Technol China, Sichuan Canc Ctr, Sichuan Canc Hosp & Inst, Dept Radiotherapy,Sch Med, Chengdu 610041, Sichuan, Peoples R China.
[37]Guangzhou Univ Chinese Med, Clifford Hosp, Dept Clin Nutr, Guangzhou 510632, Guangdong, Peoples R China.
[38]Fourth Mil Med Univ, Xijing Hosp, Dept Digest Dis, Xian 710032, Shanxi, Peoples R China.
[39]Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr Canc Hosp, Dept Hepatobiliary Surg, Beijing 100021, Peoples R China.
[40]Third Mil Med Univ, Daping Hosp, Dept Nutr, Chongqing 400042, Peoples R China.
[41]Third Mil Med Univ, Res Inst Surg, Chongqing 400042, Peoples R China.
[42]Capital Med Univ, Beijing Shijitan Hosp, Dept Gastrointestinal Surg Clin Nutr, 10 Tieyi Rd, Beijing 100038, Peoples R China.
[43]Zhengzhou Univ, Coll Publ Hlth, Dept Epidemiol, Zhengzhou 450001, Henan, Peoples R China.
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