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Xylarkarynone A and B: Two Bioactive Eremophilane Sesquiterpenes from Xylaria sp. HHY-2 期刊论文

编号：

43EF9478A953A44E149607D386D805B4
作者：

Zhu, Li#^[1]Zhang, ShengQi^[1];Wang, YiNong^[1];Wang, JiaXin^[1];Wang, ChengYao^[1];Cai, Lan*^[1]Wen, ZhaoFei^[1];Deng, Liang(邓亮)*^[2,3,4]Cai, Le(蔡乐)*^[1]
语种：

英文
期刊：

CHEMISTRY & BIODIVERSITY ISSN：1612-1872 2024 年 21 卷 7 期 ; JUL
收录：
关键词：

Xylaria sp. natural products biological activity
摘要：

A new compound xylarkarynone A (1), a first reported natural product compound xylarkarynone B (2) and eight known compounds (3-10) were isolated from Xylaria sp. HHY-2. Their structures were elucidated by spectroscopic methods, DP4+ probability analyses and electronic circular dichroism (ECD) calculations. The bioactivities of isolated compounds were assayed. Compound 1 exhibited obvious activity against A549 cells with an IC50 value of 6.12 +/- 0.28 mu M. Additionally, compound 1 showed moderate antifungal activities against Plectosphaerella cucumerina and Aspergillus niger with minimum inhibitory concentrations (MICs) of both 16 mu g/mL, which was at the same grade with positive control nystatin. Most compounds exhibited varying degrees of inhibitory activity against P. cucumerina, indicating that Xylaria sp. has potential as inhibitors against P. cucumerina.
推荐引用方式
GB/T 7714：

Zhu Li,Zhang Sheng-Qi,Wang Yi-Nong, et al. Xylarkarynone A and B: Two Bioactive Eremophilane Sesquiterpenes from Xylaria sp. HHY-2 [J].CHEMISTRY & BIODIVERSITY,2024,21(7).
APA：

Zhu Li,Zhang Sheng-Qi,Wang Yi-Nong,Wang Jia-Xin,&Cai Le.(2024).Xylarkarynone A and B: Two Bioactive Eremophilane Sesquiterpenes from Xylaria sp. HHY-2 .CHEMISTRY & BIODIVERSITY,21(7).
MLA：

Zhu Li, et al. "Xylarkarynone A and B: Two Bioactive Eremophilane Sesquiterpenes from Xylaria sp. HHY-2" .CHEMISTRY & BIODIVERSITY 21,7(2024).
入库时间：

2024/7/16 5:56:29
更新时间：

2024/7/16 5:56:29
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