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Structurally diverse diterpenoids from the seeds of Caesalpinia minax Hance and their bioactivities 期刊论文

编号：

CB03FC1D587480B53A42B426A1A962D2
作者：

Tu, WenChao#^[1,2,3,4]Ding, LinFen(丁林芬)#^[3,4,6]Song, LiuDong(宋流东)^[3,4]Li, YongJiao^[1,2];Yan, RunCheng^[1,2];Wu, Yun^[1,2];Feng, WeiYang(冯维杨)*^[5]Wu, XingDe(吴兴德)*^[1,2]
语种：

英文
期刊：

PHYTOCHEMISTRY ISSN：0031-9422 2024 年 225 卷 ; SEP
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关键词：

Caesalpinia minax Hance Fabaceae Diterpenoid alpha-Glucosidase Nitric oxide (NO)
摘要：

Eight previously undescribed diterpenoids, caesamins A-H (1-8), were separated and identified from the seeds of Caesalpinia minax Hance. Their structures were characterized by extensive spectroscopic data and X-ray crystallographic analysis. Structurally, caesamin A (1) is the first cassane-type diterpenoid with a C23 carbon skeleton containing an unusual isopropyl. Caesamin F (6) represents the first example of cleistanthane diterpenoid from the genus Caesalpinia. Caesamins B (2) and F (6) exhibited inhibitory activity against LPS-induced nitric oxide production in RAW 264.7 macrophages with IC50 values of 45.67 +/- 0.92 and 42.99 +/- 0.24 mu M, comparable to positive control 43.69 +/- 2.62 mu M of NG-Monomethyl-L-arginine. Furthermore, the chemotaxonomic significance of the isolates was discussed.
推荐引用方式
GB/T 7714：

Tu Wen-Chao,Ding Lin-Fen,Song Liu-Dong, et al. Structurally diverse diterpenoids from the seeds of Caesalpinia minax Hance and their bioactivities [J].PHYTOCHEMISTRY,2024,225.
APA：

Tu Wen-Chao,Ding Lin-Fen,Song Liu-Dong,Li Yong-Jiao,&Wu Xing-De.(2024).Structurally diverse diterpenoids from the seeds of Caesalpinia minax Hance and their bioactivities .PHYTOCHEMISTRY,225.
MLA：

Tu Wen-Chao, et al. "Structurally diverse diterpenoids from the seeds of Caesalpinia minax Hance and their bioactivities" .PHYTOCHEMISTRY 225(2024).
入库时间：

2024/7/14 18:55:24
更新时间：

2025/2/24 0:28:29
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