Cardiovascular diseases constitute a marked threat to global health, and the emergence of spatial omics technologies has revolutionized cardiovascular research. This review explores the application of spatial omics, including spatial transcriptomics, spatial proteomics, spatial metabolomics, spatial genomics, and spatial epigenomics, providing more insight into the molecular and cellular foundations of cardiovascular disease and highlighting the critical contributions of spatial omics to cardiovascular science, and discusses future prospects, including technological advancements, integration of multi-omics, and clinical applications. These developments should contribute to the understanding of cardiovascular diseases and guide the progress of precision medicine, targeted therapies, and personalized treatments.
[1]Chinese Acad Med Sci & Peking Union Med Coll, Fuwai Hosp, Natl Ctr Cardiovasc Dis, Dept Cardiac Surg, Beijing, Peoples R China.
[2]Chinese Acad Med Sci & Peking Union Med Coll, Natl Ctr Cardiovasc Dis, Fuwai Hosp, State Key Lab Cardiovasc Dis, Beijing, Peoples R China.
[3]Chinese Acad Med Sci & Peking Union Med Coll, Fuwai Hosp, Natl Ctr Cardiovasc Dis, Beijing Key Lab Preclin Res & Evaluat Cardiovasc I, Beijing, Peoples R China.
[4]Kunming Med Univ, Fuwai Yunnan Hosp, Chinese Acad Med Sci, Dept Cardiac Surg,Affiliated Cardiovasc Hosp, Kunming, Peoples R China.
[5]Chinese Acad Med Sci, Fuwai Hosp, Shenzhen Key Lab Cardiovasc Dis, Shenzhen, Peoples R China.
(8.0+极速模式)